cyclosporine-for-dogs[/caption]Cyclosporine (Modified) Generic To Atopica
Cyclosporine (Modified) capsules, a generic to Atopica, are used for the treatment of atopic dermatitis in dogs, which is a non-contagious skin disease characterized by chronic inflammation of the skin. While its not approved by the FDA for cats, it is commonly prescribed by veterinarians to treat cats. Cyclosporine requires a prescription from your veterinarian.
Cats (6 months or older and weighing 4 lbs. or more), Dogs (6 months or older and weighing 4 lbs. or more)
- Cyclosporine treats atopic dermatitis, which can come with any of the following symptoms: scratching, licking, chewing, skin infections, hair loss, bad odors, and sleepless nights
- Safe and more affordable alternative to steroid shots
Cyclosporine targets cells in the immune system that cause the allergic reaction in your pet. Dosage varies, and can taper off to fewer doses after several weeks. Consult with your veterinarian for specific treatment details.
Consult your veterinarian about possible side effects or drug interactions.
Atopica (Novartis Animal Health)
Cyclosporine (sy-klo-spor'-een) Modified capsule
Tell your veterinarian if your pet has liver disease, kidney disease, cancer, high blood pressure, a viral, bacterial or fungal infection, or any other serious or chronic condition. Tell your veterinarian if your pet is pregnant or lactating, and if you plan to breed your pet.
Give cyclosporine modified exactly as directed by your veterinarian. If you do not understand these directions, ask your veterinarian or pharmacist to explain them to you. Always give cyclosporine modified 2 hours before or 2 hours after a meal. Allow plenty of water for the pet to drink. Do not remove a capsule from the blister pack until required for use. When the capsule is removed from the blister pack there is a characteristic, noticeable smell which is normal. Your veterinarian may want your pet to have regularly scheduled blood tests during treatment to monitor effectiveness and side effects. Store cyclosporine modified at room temperature away from moisture and heat.
Give the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and give the next regularly scheduled dose. Do not give a double dose unless otherwise directed by your veterinarian.
The safe use in breeding, pregnant or lactating dogs has not been determined. Do not use cyclosporine modified in dogs with known allergy to the medication. The drug should not be used in dogs with kidney disease, stomach ulcers, and certain blood disorders. Prolonged use of cyclosporine modified can result in bacterial or fungal infection related to a decreased effect of the immune system.
If any of the following serious side effects occur, stop giving cyclosporine modified and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing, swelling of the lips, tongue or face, and hives). Other less serious side effects may occur. Continue giving cyclosporine modified and talk to your veterinarian if your pet develops vomiting, soft stools or diarrhea, muscle cramps, muscle weakness, loss of appetite, and change of hair coat. Other side effects may occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to the animal.
Cyclosporine
Uses
Cyclosporine is indicated for the control of atopica dermatitis in dogs weighing at least 4 lbs body weight.
Dosage and Administration
Cyclsporine (Atopica) should be given according to your veterinarian’s instructions. Do not change the way you give Cyclosporine without speaking with your veterinarian first. The recommended dose of Cyclosporine is it should be given initially as a 5 mg/kg/day (3.3-6.7 mg/kg/day) single daily dose for 30 days. Following this initial daily treatment period, the Cyclosporine dose may be tapered by decreasing the frequency of dosing to every other day or two times a week until a minimum frequency is reached, which will maintain the desired therapeutic effect. Cyclosporine should be given on an empty stomach, so please wait at least one hour before or two hours after a meal before giving Cyclosporine.
Missed Dose?
If a dose of Cyclosporine (Atopica) is missed, the next dose should be administered as soon as possible, but do NOT double the dose.
Possible Side Effects
Cyclosporine (Atopica) may cause some side effects. Most common side effects of Cyclosporine involve the digestive including vomiting, and diarrhea. Other possible side effects of Cyclosporine:
- Persistent Otitis Externa (swimmer’s ear)
- Urinary Tract Infection
- Anorexia
- Lethargy
- Gingival Hyperplasia (overgrowth of gums)
- Lymphadenopathy (swelling of lymph nodes)
It is important to stop the medication and immediately contact your veterinarian if you think your dog has any medical problems or side effects while taking Cyclosporine.
Precautions
Cyclosporine is contraindicated for use in dogs with a history of neoplasia. Cyclosporine (Atopica) is a potent systemic immunosuppressant that may cause the susceptibility to infection and the development of neoplasia. Gastrointestinal problems and gingival hyperplasia may occur at the initial recommended dose.
Cyclosporine should not be administered to dogs less than 6 months of age or less than 4 lbs of body weight. It should also not be used in breeding dogs, pregnant or lactating female dogs.
The effect of Cyclosporine use on dogs with compromised renal functions has not been studied so Cyclosporine should be used with caution in dogs with renal insufficiency.
Atopica is not for human use. Keep this drug and all drugs out of reach of children. For use in dogs only.
Storage
Cyclosporine (Atopica) should be stored and dispensed in the original unit-dose container at controlled room temperature between 59 and 77°F (15-25°C).
Drug Interactions
Cyclosporine should be used with caution when given with drugs that affect the P-450 enzyme system. Simultaneous administration of cyclosporine with drugs that suppress the P-450 enzyme system, such as ketoconazole, may lead to increased plasma levels of cyclosporine.
Signs of Toxicity/Overdose
Overdose of Cyclosporine (Atopica) may cause:
- Loss of appetite
- Vomiting
- Diarrhea
- Increased thirst
- Increase urination
- Jaundice
- Lethargy
If you suspect or know you dog has had an overdose, please contact your veterinarian an emergency vet clinic, or the Pet Poison Helpline at (855) 213-6680 immediately..
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